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Writer's pictureAndrew Damian, PsyD

What is the Nocebo Effect?

The nocebo effect is a phenomenon in which an individual experiences negative side effects or symptoms as a result of believing that they are taking a medication or receiving a treatment, even when they are not. This effect can occur when an individual expects to experience negative side effects or when they are told about the potential for negative side effects by a healthcare provider or other source.



The nocebo effect is the opposite of the placebo effect, which is when an individual experiences positive effects or symptoms as a result of believing that they are taking a medication or receiving a treatment, even when they are not. The placebo effect is often used in research studies as a control to measure the effectiveness of a treatment or medication.


The nocebo effect can have significant implications for mental health treatment, as an individual's beliefs and expectations about a treatment can impact their response to it. For example, if an individual is told that a treatment may cause certain side effects or that it may not be effective, they may be more likely to experience those side effects or to perceive the treatment as not being effective.


In the context of biofeedback and neurofeedback, the nocebo effect can be particularly relevant. Biofeedback and neurofeedback are therapies that involve providing feedback on an individual's physiological responses, such as brain activity, heart rate, or muscle tension, in order to teach them to self-regulate those responses. If an individual expects or is told that the therapy may not be effective or may cause negative side effects, they may be more likely to experience those negative effects or to perceive the therapy as not being helpful.


To minimize the nocebo effect in biofeedback and neurofeedback, it is important for healthcare providers to be transparent and honest with their patients about the potential risks and benefits of the therapy, as well as to provide clear explanations about the therapy and how it works. It is also important for patients to have realistic expectations about the therapy and to be open to the possibility of experiencing both positive and negative effects during the course of treatment.


In conclusion, the nocebo effect is a phenomenon in which an individual experiences negative side effects or symptoms as a result of believing that they are taking a medication or receiving a treatment. It can have significant implications for mental health treatment, including biofeedback and neurofeedback, and it is important for healthcare providers and patients to be aware of this effect and to take steps to minimize it.

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